NFL Betting: The Best Online Sportsbooks in Missouri for Football

Missouri just pulled off one of the closest sports betting votes in American history. Voters approved Amendment 2 in November 2024 by a razor-thin 50.05% to 49.95% margin, and now the state is racing toward a December 1, 2025 statewide launch. Sports betting is legal, but not yet live. You can pre-register with all nine operators and lock in bonuses, but you can't place real-money bets until December 1. Until then, Daily Fantasy Sports platforms like Underdog and FanDuel DFS are the only legal in-state NFL wagering options at 18+.

Read more: NFL Betting: The Ultimate Guide for the 2025/2026 Football Season

Current Legal Status: Pre-Launch (November 2025)

Sports betting is legal BUT NOT YET LIVE in Missouri. Voters approved Amendment 2 in November 2024; the Missouri Gaming Commission officially launches all operators on December 1, 2025.

Here's what's happening NOW (November 2025):

• Pre-registration open: All 9 licensed operators accepting new accounts since November 17, 2025
• Welcome bonuses locked in: FanDuel offers $400 in bonus bets ($100 immediately + $300 on launch day); others offering similar pre-launch promos
• No real-money wagering yet: Pre-registered accounts are "frozen" until December 1
• Age requirement: 21+ only

9 Licensed Operators (All Pre-Registering): Untethered licenses (2): DraftKings, Circa. Casino/team-partnered (7): FanDuel, Caesars, BetMGM, Fanatics, Underdog, theScore Bet, Bet365.

Expected December 1, 2025 Launch: Full online betting goes live across all 9 operators, combined welcome bonuses expected to exceed $3,500+ (FanDuel alone: $400), retail betting at Missouri casinos + pro sports venues simultaneously, tax revenue funds education and problem gambling programs.

Daily Fantasy Sports: Legal NOW for NFL Wagering

Until December 1, 2025, DFS is Missouri's ONLY legal online NFL wagering option (age 18+, statewide access).

• Underdog Fantasy: Statewide legal (18+ age). NFL focus: Daily contest drafts on all NFL games. Welcome: Play $5, Get $50.
• FanDuel DFS: Missouri legal (18+ age). Formats: DFS daily contests, pick'em available. Welcome bonuses available.
• DraftKings DFS: Missouri legal (18+ age). Full NFL slate daily contests.
• PrizePicks: NOT available in Missouri (restricted state). Missouri explicitly prohibits over/under or "higher/lower" player prop contests.
• Why DFS is valuable until December 1: Legal statewide with 18+ access (3 years younger than 21+ sportsbooks), instant online access (no retail visit needed), daily NFL contests with significant prize pools.

Shurzy tip: Missouri's launch is so close you can taste it. If you live near the Kansas border, you can also cross state lines and use Kansas sportsbooks that are already live. But honestly? Just wait two weeks. December 1 is going to be massive.

What to Expect December 1, 2025

When legal sportsbooks launch, here's what happens: BetMGM, Caesars, FanDuel, and DraftKings will offer industry-leading odds and same-game parlays. Underdog Sportsbook becomes the first major DFS provider entering the retail sportsbook space. Circa Sports debuts innovative features (likely strong parlay/futures focus). Pre-registered accounts go live with $400+ in locked-in bonuses activating immediately. Tax rate is 10% on gross revenue funding education.

Read more: Best Sports Betting Bonuses and Promos in Missouri

NFL Teams & Betting Dynamics

Missouri's proximity to Kansas City Chiefs (Super Bowl champions), St. Louis Cardinals (regional baseball interest), and access from Kansas/Illinois creates intense multi-sport wagering interest. December 1 launch coincides with NFL playoff race ramp-up and NBA/NHL postseason approaches, making it perfect timing for maximum early betting volume.

Read more: Everything You Need to Know About NBA Prop Betting

Strategic Recommendation

Use DFS platforms (Underdog, FanDuel DFS) for statewide 18+ NFL wagering. Pre-register with all 9 operators to lock in bonuses before December 1. Consider crossing into Kansas (FanDuel, DraftKings, Caesars live now) for traditional sportsbooks if near border.

Nine competing operators will offer industry-leading bonuses and competitive odds. Line shopping becomes critical with full market competition. FanDuel's $400 pre-launch bonus is one of largest single-operator promos ever.

Shurzy tip: Missouri's about to go from zero to nine sportsbooks overnight. That's the kind of competition that creates value for bettors. Pre-register everywhere, lock in every bonus, and get ready to line shop like your bankroll depends on it (because it does).

Read more: NHL Betting: The Ultimate Guide for the 2025/2026 Hockey Season

Responsible Gambling in Missouri

Missouri will provide comprehensive responsible gaming resources when sportsbooks launch. All operators will offer deposit limits, session time limits, and self-exclusion options.

Get Help: If you or someone you know struggles with problem gambling, contact the National Problem Gambling Helpline at 1-800-GAMBLER (1-800-426-2537), available 24/7, free, and confidential.

Final Take: Missouri's Historic Launch

Missouri sits at the threshold of market transformation. Currently pre-launch with DFS as the only legal online NFL option, but December 1, 2025 launch will introduce 9 competing operators with combined bonuses exceeding $3,500+. This represents one of America's most anticipated launches given narrowest voter approval margin (50.05%) and the region's intense sports fandom.

Shurzy tip: Pre-register now, claim your bonuses, and get ready for one of the biggest launch days in sports betting history.